I-Tofacitinib Intermediate 1,4-Chloro-7-p-toluenesulfonyl-7H pyrrolo [2,3-d] pyrimidine CAS No. 479633-63-1

Ifomula yamangqamuzana yalokhu okumaphakathi yi-C13H10ClN3O2S, futhi isisindo sayo samangqamuzana ngu-307.755.Ukwakheka kwayo okunembile kwamangqamuzana kwenza ukukhiqizwa okuphumelelayo nokuhlanzeka okuphezulu kwe-tofacitinib.Ngakho-ke, i-tofacitinib ephakathi kwe-1,4-chloro-7-p-toluenesulfonyl-7H pyrrolo[2,3-d]pyrimidine iyingxenye ebalulekile embonini yezemithi ukuze inikeze ukwelashwa okuphumelelayo kwezifo ezizimele.

Imikhiqizo yethu ikhiqizwa kusetshenziswa izinqubo zesimanje ukuze kuqinisekiswe ikhwalithi ephezulu nokuvumelana.Siyakuqonda ukubaluleka kokuba nabaphakathi abathembekile nabamsulwa ekukhiqizeni imithi, yingakho sizibophezele ekugcineni izindinganiso eziqinile phakathi nenqubo yethu yokukhiqiza.I-tofacitinib yethu emaphakathi engu-1,4-chloro-7-p-toluenesulfonyl-7H pyrrolo[2,3-d]pyrimidine ihlolwa ngokuqinile, ukuqina nokuphepha ukuze kuvunyelwe amakhasimende ethu Ukuqiniseka ngokuthembeka kokuhlanganiswa kwe-tofacitinib ngezinga elikhulu.