Incazelo
I-Topirastat ephakathi kwe-2-cyanoisonicotinic acid, i-CAS No. 161233-97-2.Lo mkhiqizo waziwa nangamanye amagama: 2-cyanopyridine-4-carboxylic acid, 2-cyano-4-pyridinecarboxylic acid, kanye 4-pyridinecarboxylic acid, 2-cyano-.Ifomula yamangqamuzana yale nhlanganisela ephakathi yi-C7H4N2O2 futhi isisindo samangqamuzana yi-148.1189.Kuyingxenye ebalulekile ekuhlanganisweni kwe-topirastat (isidakamizwa esisetshenziselwa ukwelapha i-hyperuricemia ezigulini ze-gout).
I-2-Cyanoisonicotinic acid idlala indima ebalulekile ekukhiqizeni i-topirastat, esebenza ngokuvimbela i-xanthine oxidase, i-enzyme ebandakanyeka ekukhiqizeni i-uric acid.Ngenxa yalokho, amazinga e-uric acid egazini ehla, ekhulula izimpawu zeziguli ze-gout.Lesi sithako esiphakathi siyisithako esiyinhloko enqubweni yokukhiqiza i-topirastat, okwenza kube yingxenye ebalulekile yemboni yezemithi.
Khetha Thina
I-JDK ingumnikazi wezindawo zokukhiqiza zekilasi lokuqala kanye nempahla yokuphatha Ikhwalithi, eqinisekisa ukuhlinzekwa okuzinzile kwama-API intermediates.Ithimba lochwepheshe liqinisekisa i-R&D ngomkhiqizo.Ngokuphikisana nakho kokubili, sifuna i-CMO & CDMO emakethe yasekhaya neyamazwe ngamazwe.